June 14, 2026

College football odds, picks, lines for Week 12: Advanced computer model loving Missouri, Ohio State

Just two full weeks remain in the regular season and about 10 teams are still legitimately in the conversation to make the College Football Playoff. The latest Week 12 college football odds show several of them as huge favorites, but No. 9 West Virginia (-5) gets a tough road trip to Oklahoma State, No. 3 Notre Dame (-9.5) will battle No. 13 Syracuse at Yankee Stadium and No. 8 Washington State (-10) should be tested by an Arizona squad that has won two straight. With tight college football odds like those, and larger spreads like No. 5 Georgia (-43.5) vs. Massachusetts, you’ll want to check out the top Week 12 college football picks and predictions from SportsLine’s proven computer model.  The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen massive returns. Over the past three years, this proprietary computer…

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