May 3, 2026

Ohio State vs. Cincinnati odds, predictions: 2019 college football picks from expert who's 13-0 on Buckeyes games


One week after an impressive debut by coach Ryan Day and quarterback Justin Fields, the fifth-ranked Ohio State Buckeyes (1-0) will try to keep the momentum going on Saturday against the Cincinnati Bearcats (1-0) in Columbus. Last week against Florida Atlantic, the Buckeyes jumped out to a 28-0 first quarter lead and were never threatened. Meanwhile, Ohio State’s much-maligned defense held the Owls to minus-14 total yards in the first half and 228 overall. Two nights earlier, the Bearcats led wire-to-wire in a 24-14 victory over UCLA in Cincinnati. Kickoff is 12 p.m. ET. The Buckeyes are 16-point favorites in the latest Ohio State vs. Cincinnati odds, while the over-under is 53. Before making any Ohio State vs. Cincinnati picks of your own, be sure to see the college football predictions from SportsLine data scientist Stephen Oh.  The renowned co-founder of Accuscore, Oh simulates each game 10,000 times using the…

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