Getty Images A high-profile Big Ten matchup is set to take place in Columbus, Ohio on Saturday afternoon. The No. 4 Ohio State Buckeyes welcome the No. 19 Purdue Boilermakers to Ohio Stadium, with lofty stakes for both sides. Ohio State is a top-five team in the country with a 6-0 conference record and a mark of 8-1 overall. Purdue is 6-3 overall and ranked in the top-20 after an upset win over Michigan State last week. Kickoff is at 3:30 p.m. ET. Caesars Sportsbook lists the Buckeyes as 21-point favorites, while the over-under, or total number of points Vegas thinks will be scored, is 62.5 in the latest Purdue vs. Ohio State odds. Before you make any Ohio State vs. Purdue picks and college football predictions, you need to see what SportsLine’s advanced computer model has to say. The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over…
Continue Reading: Ohio State vs. Purdue odds, line, spread: 2021 college football picks, Week 11 predictions from proven model
