42 Ohio State vs Michigan State, November 20, 2021 COLUMBUS, Ohio — Ohio State football will takes its smallest point spread of the season into The Game at Michigan on Saturday. Circa Sports established the Buckeyes as a 7-point favorite in its opening line on Saturday. Ohio State had been favored by 14 or more points at kickoff in each of its first 11 games. Note to readers: if you purchase something through one of our affiliate links we may earn a commission.
Continue Reading: What is Ohio State football’s point spread over Michigan in The Game? College betting lines
