June 15, 2026

March Madness: Loyola-Chicago vs. Ohio State odds, picks and predictions

The 2022 NCAA Tournament resumes Friday with a South Region showdown between the No. 10 seed Loyola-Chicago Ramblers (25-7) and the seventh-seeded Ohio State Buckeyes (19-11). Tip-off at PPG Paints Arena in Pittsburgh is scheduled for 12:15 p.m. ET (CBS). Below, we look at the Loyola-Chicago vs. Ohio State odds and lines, and make our expert college basketball picks, predictions and bets. Loyola-Chicago earned its “Big Dance” berth by winning the Missouri Valley Conference Tournament for the third time in the last five seasons, including a second straight. The Rambles rank 24th in adjusted-net efficiency (according to KenPom) but played the 107th-toughest schedule, according to USA TODAY’s Jeff Sagarin.. Ohio State clinched an at-large bid despite having fewer than 20 wins for the first time since 2017. The Buckeyes haven’t advanced past the second round of the NCAA tourney in all four trips under fifth-year head coach Chris Holtmann. The…

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