June 15, 2026

Ohio State vs. Penn State prediction, odds: 2022 Week 9 college football picks, best bets from proven model

USATSI The No. 13 Penn State Nittany Lions (6-1) host the No. 2 Ohio State Buckeyes in an important Big Ten showdown on Saturday afternoon. Both of these teams have explosive and exciting offenses. The Buckeyes are first in the conference in scoring (49.6) and total offense (517.4). Meanwhile, the Nittany Lions are fourth in scoring (33.4) and seventh in total offense (423.6). The Buckeyes are 4-2 against the spread when facing FBS competition this year while Penn State has a 4-3 ATS mark.  Kickoff from Beaver Stadium in University Park is set for noon ET. Caesars Sportsbook lists the Buckeyes as 15.5-point favorites in the latest Ohio State vs. Penn State odds. The over/under for total points is set at 60.5. Before locking in any Penn State vs. Ohio State picks, you need to see the college football predictions and betting advice from SportsLine’s advanced computer model. The SportsLine…

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