June 25, 2026

Ohio State vs. Michigan prediction, odds, line: 2022 Week 13 college football picks, best bets by proven model

The second-ranked Ohio State Buckeyes are seeking a sixth Big Ten Conference Championship Game appearance when they take on the defending Big Ten East Division champion and No. 3 Michigan Wolverines in The Game on Saturday. The Buckeyes (11-0, 8-0) have not lost a Big Ten game at Ohio Stadium since the 2015 season, and have won 29 consecutive conference home games. The Wolverines (11-0, 8-0), who look to snap a nine-game losing streak in Columbus, last won at Ohio Stadium in 2000, a 38-26 triumph to capture the conference championship. This will be the 25th time that Michigan and Ohio State meet in a top-10 matchup. The Buckeyes hold a 12-10-2 edge in those games. <span class="image" data-attrib="Provided by CBS Sports" data-caption="Oct 24, 2015; Atlanta, GA, USA; Georgia Tech Yellow Jackets helmet on the field before a game against the Florida State Seminoles at Bobby Dodd Stadium.” data-id=”56″ data-m=”{"i":56,"p":55,"n":"openModal","t":"articleImages","o":1}”> ©…

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