Getty Images No. 25 Ohio State (5-1) heads into Cameron Indoor Stadium as they match up against No. 17 Duke (6-2) in a ACC/Big Ten Challenge game on Wednesday night. The Blue Devils had their four-game win streak halted in their previous contest. Duke lost to No. 5 Purdue 75-56 in the 2022 Phil Knight Legacy Championship Game. Meanwhile, Ohio State has won two straight games, including an 80-73 win over Texas Tech in the 2022 Maui Invitational. Ohio State is 3-3 against the spread, while Duke is 4-4 ATS this season. Tip-off from the Cameron Indoor Stadium in Durham, N.C. is set for 7:15 p.m. ET. The Blue Devils are 5.5-point favorites in the latest Ohio State vs. Duke odds from Caesars Sportsbook, while the over/under for total points scored is 135. Before locking in any Ohio State vs. Duke picks, be sure to see the college basketball predictions…
Continue Reading: Duke vs. Ohio State prediction, odds, line: 2022 College basketball picks, Nov. 30 best bets from proven model