June 26, 2026

Ohio State vs. Michigan State odds, spread: 2023 college football picks, Week 11 predictions from proven model

USATSI The Michigan State Spartans (3-6) will try to spring one of the biggest upsets in Big Ten history when they face the top-ranked Ohio State Buckeyes (9-0) on Saturday night. Michigan State had dropped six consecutive games prior to its 20-17 win over Nebraska last week. It was the team’s first win under interim head coach Harlon Barnett, who took over when Mel Tucker was fired at the end of September. Ohio State remained perfect on the season with its 35-16 win at Rutgers last week, wrapping up three road games in a four-week stretch.  Kickoff is set for 7:30 p.m. ET on Saturday at Ohio Stadium. The Buckeyes are favored by 31.5 points in the latest Ohio State vs. Michigan State odds, while the over/under is set at 47 points, per SportsLine consensus. Before entering any Michigan State vs. Ohio State picks, you’ll want to see the college…

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