May 17, 2026

College football odds, lines, schedule for Week 5: Ohio State-Penn State, Stanford-Notre Dame are close

With one month of the 2018 college football season in the books, we have begun to see our fair share of upsets take place. Are more on tap in Week 5? The first thing we need to do in order to answer that question is take a look at the opening lines released out of Las Vegas now that a new week has begun. There are some major games on the Week 5 slate, including one showdown that could go a long way to determining the top team in the Big Ten and another that will serve to answer whether the two teams going head-to-head are for-real title contenders this season. Those games lead off the “lines you need to know” below. Lines you need to know Ohio State at Penn State (+3.5): These might be the two best teams in the Big Ten East this season, and the Nittany…

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