No. 1 Mike Vrabel, 1995: 26 tackles for a loss No. 2 Andy Katzenmoyer, 1996: 23 tackles for a loss No. 3 Ryan Shazier, 2013: 22.5 tackles for a loss No. 4 Chase Young, 2019: 21 tackles for a loss No. 4 Joey Bosa, 2014: 21 tackles for a loss No. 6 Will Smith, 2003: 20 tackles for a loss No. 6 Mike Vrabel, 1994: 20 tackles for a loss No. 6 Matt Finkes, 1994: 20 tackles for a loss No. 9 Matt Wilhelm, 2002: 19.5 tackles for a loss No. 10 Matt Finkes, 1995: 19 tackles for a loss No. 11 Jason Simmons, 1991: 18.5 tackles for a loss No. 12 Mike Vrabel, 1996: 18 tackles for a loss No. 13 Ryan Shazier, 2012: 17 tackles for a loss No. 14 Malik Harrison, 2019: 16.5 tackles for a loss No. 14 Darron Lee, 2014: 16.5 tackles for a loss No. 14 A.J. Hawk, 2005: 16.5 tackles for a loss
Continue Reading: All-time statistical leaders in Ohio State football history: Defense
