June 14, 2026

First look: Penn State at Ohio State odds and lines

The No. 17 Penn State Nittany Lions (5-2, 2-2 Big Ten) meet the No. 5 Ohio State Buckeyes (6-1, 4-0) at Ohio Stadium in Columbus. Kickoff is scheduled for 7:30 p.m. ET. Below, we look at the Penn State vs. Ohio State odds and lines; check back for our college football picks and predictions. The Nittany Lions were upset at home by Illinois at Beaver Stadium on Saturday, falling 20-18 in 9 overtimes in the new nonsense overtime rules. Penn State has lost two in a row and is 1-3 against the spread (ATS) across the past four outings. The Buckeyes roughed up Indiana on the road, winning 54-7 to easily cover as 21-point favorites. That’s four straight covers, and five consecutive victories since a setback to Oregon Sept. 11. Ohio State has scored 52 or more points in four straight outings. Rankings according to the AFCA Coaches Poll powered by…

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